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Enzymatic Basis for Overproduction of Tryptophan and Its Metabolites in Hansenula polymorpha Mutants

3-Deoxy-d-arabinoheptulosonate 7-phosphate (DAHP) synthetase and anthranilate synthetase are key regulatory enzymes in the aromatic amino acid biosynthetic pathway. The DAHP synthetase activity of Hansenula polymorpha was subject to additive feedback inhibition by phenylalanine and tyrosine but not...

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Denenu, Emmanuel O., Demain, Arnold L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1981
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC244043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16345845/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.42.3.497-501.1981
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