Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142

AIDS-associated, CCR5-tropic (R5) HIV-1 clones, isolated from a patient that never developed CXCR4-tropic HIV-1, replicate to a greater extent and cause greater cytopathic effects than R5 HIV-1 clones isolated before the onset of AIDS. Previously, we showed that HIV-1 Env substantially contributed t...

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Bibliografiske detaljer
Main Authors: Olivieri, Kevin C, Scoggins, Robert M, Broderick, Brooks, Powell, Maria LC, Alexander, Melissa A, Hammarskjöld, Marie-Louise, Rekosh, David, Camerini, David
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440386/
https://ncbi.nlm.nih.gov/pubmed/18510766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-42
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