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Total Synthesis of (±)-Mitorubrinic Acid

(±)-Mitorubrinic acid, a member of the azaphilone family of natural products, has been constructed in 12 steps. Key aspects of the synthesis include elaboration and oxidative dearomatization of an isocoumarin intermediate to provide the azaphilone nucleus with a disubstituted, unsaturated carboxylic...

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Hlavní autoři: Marsini, Maurice A., Gowin, Kristoffer M., Pettus, Thomas R. R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440338/
https://ncbi.nlm.nih.gov/pubmed/16869640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/o10610993
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