Altered regulation of platelet-derived growth factor receptor-α gene-transcription in vitro by spina bifida-associated mutant Pax1 proteins

Mouse models show that congenital neural tube defects (NTDs) can occur as a result of mutations in the platelet-derived growth factor receptor-α gene (PDGFRα). Mice heterozygous for the PDGFRα-mutation Patch, and at the same time homozygous for the undulated mutation in the Pax1 gene, exhibit a high...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Joosten, Paul H. L. J., Hol, Frans A., van Beersum, Sylvia E. C., Peters, Heiko, Hamel, Ben C. J., Afink, Gijs B., van Zoelen, Everardus J. J., Mariman, Edwin C. M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 1998
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC24395/
https://ncbi.nlm.nih.gov/pubmed/9826722
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