Altered regulation of platelet-derived growth factor receptor-α gene-transcription in vitro by spina bifida-associated mutant Pax1 proteins

Mouse models show that congenital neural tube defects (NTDs) can occur as a result of mutations in the platelet-derived growth factor receptor-α gene (PDGFRα). Mice heterozygous for the PDGFRα-mutation Patch, and at the same time homozygous for the undulated mutation in the Pax1 gene, exhibit a high...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Joosten, Paul H. L. J., Hol, Frans A., van Beersum, Sylvia E. C., Peters, Heiko, Hamel, Ben C. J., Afink, Gijs B., van Zoelen, Everardus J. J., Mariman, Edwin C. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24395/
https://ncbi.nlm.nih.gov/pubmed/9826722
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky