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A role for the RISK pathway and K(ATP) channels in pre- and post-conditioning induced by levosimendan in the isolated guinea pig heart

BACKGROUND AND PURPOSE: Myocardial reperfusion injury prevents optimal salvage of the ischaemic myocardium, and adjunct therapy that would significantly reduce reperfusion injury is still lacking. We investigated whether (1) the heart could be pre- and/or post-conditioned using levosimendan (levosim...

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Detalhes bibliográficos
Main Authors: du Toit, E F, Genis, A, Opie, L H, Pollesello, P, Lochner, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438987/
https://ncbi.nlm.nih.gov/pubmed/18297097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.52
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