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A role for the RISK pathway and K(ATP) channels in pre- and post-conditioning induced by levosimendan in the isolated guinea pig heart

BACKGROUND AND PURPOSE: Myocardial reperfusion injury prevents optimal salvage of the ischaemic myocardium, and adjunct therapy that would significantly reduce reperfusion injury is still lacking. We investigated whether (1) the heart could be pre- and/or post-conditioned using levosimendan (levosim...

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Autors principals: du Toit, E F, Genis, A, Opie, L H, Pollesello, P, Lochner, A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438987/
https://ncbi.nlm.nih.gov/pubmed/18297097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.52
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