The mutationally activated Met receptor mediates motility and metastasis

Mutations in Met have been identified in human papillary renal carcinomas. We have shown previously that these mutations deregulate the enzymatic activity of Met and that NIH 3T3 cells expressing mutationally activated Met are transformed in vitro and are tumorigenic in vivo. In the present investig...

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Main Authors: Jeffers, Michael, Fiscella, Michele, Webb, Craig P., Anver, Miriam, Koochekpour, Shahriar, Vande Woude, George F.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1998
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC24388/
https://ncbi.nlm.nih.gov/pubmed/9826715
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