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The mutationally activated Met receptor mediates motility and metastasis

Mutations in Met have been identified in human papillary renal carcinomas. We have shown previously that these mutations deregulate the enzymatic activity of Met and that NIH 3T3 cells expressing mutationally activated Met are transformed in vitro and are tumorigenic in vivo. In the present investig...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jeffers, Michael, Fiscella, Michele, Webb, Craig P., Anver, Miriam, Koochekpour, Shahriar, Vande Woude, George F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24388/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826715/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14417
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