Large-scale modulation of thermodynamic protein folding barriers linked to electrostatics

Protein folding barriers, which range from zero to the tens of RT that result in classical two-state kinetics, are primarily determined by protein size and structural topology [Plaxco KW, Simons KT, Baker D (1998) J Mol Biol 277:985–994]. Here, we investigate the thermodynamic folding barriers of tw...

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Bibliografiske detaljer
Main Authors: Halskau, Øyvind, Perez-Jimenez, Raul, Ibarra-Molero, Beatriz, Underhaug, Jarl, Muñoz, Victor, Martinez, Aurora, Sanchez-Ruiz, Jose M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438433/
https://ncbi.nlm.nih.gov/pubmed/18550823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709881105
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