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Biologically active Phytophthora mating hormone prepared by catalytic asymmetric total synthesis

A Phytophthora mating hormone with an array of 1,5-stereogenic centers has been synthesized by using our recently developed methodology of catalytic enantioselective conjugate addition of Grignard reagents. We applied this methodology in a diastereo- and enantioselective iterative route and obtained...

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Detalhes bibliográficos
Main Authors: Harutyunyan, Syuzanna R., Zhao, Zhijian, den Hartog, Tim, Bouwmeester, Klaas, Minnaard, Adriaan J., Feringa, Ben L., Govers, Francine
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438403/
https://ncbi.nlm.nih.gov/pubmed/18559862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709289105
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