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Thrombogenic collagen-mimetic peptides: Self-assembly of triple helix-based fibrils driven by hydrophobic interactions

Collagens are integral structural proteins in animal tissues and play key functional roles in cellular modulation. We sought to discover collagen model peptides (CMPs) that would form triple helices and self-assemble into supramolecular fibrils exhibiting collagen-like biological activity without pr...

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Hlavní autoři: Cejas, Mabel A., Kinney, William A., Chen, Cailin, Vinter, Jeremy G., Almond, Harold R., Balss, Karin M., Maryanoff, Cynthia A., Schmidt, Ute, Breslav, Michael, Mahan, Andrew, Lacy, Eilyn, Maryanoff, Bruce E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438399/
https://ncbi.nlm.nih.gov/pubmed/18559857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800291105
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