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poolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening

BACKGROUND: A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in drug discovery involves testing a large number of compounds in a biological assay to identify active compounds. Normally, molecu...

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Hlavní autoři: Kainkaryam, Raghunandan M, Woolf, Peter J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438324/
https://ncbi.nlm.nih.gov/pubmed/18513431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-256
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