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A new pooling strategy for high-throughput screening: the Shifted Transversal Design

BACKGROUND: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and false negatives are a major concern. Pooling constitutes a natural solution: it reduces the number of tests, while provid...

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Detalhes bibliográficos
Autor principal: Thierry-Mieg, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409803/
https://ncbi.nlm.nih.gov/pubmed/16423300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-28
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