Enrichment of C-Terminal Fragments in TAR DNA-Binding Protein-43 Cytoplasmic Inclusions in Brain but not in Spinal Cord of Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

TAR DNA-binding protein (TDP-43) has been recently described as a major pathological protein in both frontotemporal dementia with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral sclerosis. However, little is known about the relative abundance and distribution of different pathological...

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Main Authors: Igaz, Lionel M., Kwong, Linda K., Xu, Yan, Truax, Adam C., Uryu, Kunihiro, Neumann, Manuela, Clark, Christopher M., Elman, Lauren B., Miller, Bruce L., Grossman, Murray, McCluskey, Leo F., Trojanowski, John Q., Lee, Virginia M.-Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2008
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438296/
https://ncbi.nlm.nih.gov/pubmed/18535185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080003
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