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Structural requirements for the cytoprotective actions of mono-unsaturated fatty acids in the pancreatic β-cell line, BRIN-BD11

Background and purpose: Exposure of pancreatic β-cells to long-chain free fatty acids leads to differential responses according to the chain length and degree of unsaturation. In particular, long-chain saturated molecules such as palmitate (C16:0) cause apoptosis, whereas equivalent mono-unsaturated...

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Detalhes bibliográficos
Main Authors: Dhayal, S, Welters, H J, Morgan, N G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438256/
https://ncbi.nlm.nih.gov/pubmed/18297101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.43
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