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Indomethacin promotes nitric oxide function in the ductus arteriosus in the mouse

BACKGROUND AND PURPOSE: Prenatal patency of ductus arteriosus is maintained by prostaglandin (PG) E(2) in concert with nitric oxide (NO) and carbon monoxide (CO). Accordingly, we have previously found that NO activity increases upon deletion of either COX. Here, we have examined whether COX inhibiti...

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Main Authors: Sodini, D, Baragatti, B, Barogi, S, Laubach, V E, Coceani, F
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438253/
https://ncbi.nlm.nih.gov/pubmed/18297107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.36
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