Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth

The assumption that genes encoding tyrosine kinase receptors could play a role in human cancers has been confirmed by the identification of oncogenic mutations in the kinase domain of RET and KIT. Recently, homologous residues were found mutated in MET, in papillary renal carcinomas (PRCs). The link...

Descripció completa

Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Bardelli, Alberto, Longati, Paola, Gramaglia, Daniela, Basilico, Cristina, Tamagnone, Luca, Giordano, Silvia, Ballinari, Dario, Michieli, Paolo, Comoglio, Paolo M.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1998
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24381/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14379
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!