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Identification of morc (microrchidia), a mutation that results in arrest of spermatogenesis at an early meiotic stage in the mouse

The microrchidia, or morc, autosomal recessive mutation results in the arrest of spermatogenesis early in prophase I of meiosis. The morc mutation arose spontaneously during the development of a mouse strain transgenic for a tyrosinase cDNA construct. Morc −/− males are infertile and have grossly re...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Watson, Mark L., Zinn, Andrew R., Inoue, Norimitsu, Hess, Karl D., Cobb, John, Handel, Mary Ann, Halaban, Ruth, Duchene, Clark C., Albright, George M., Moreadith, Randall W.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24378/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826705/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14361
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