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Altered peptide ligands act as partial agonists by inhibiting phospholipase C activity induced by myasthenogenic T cell epitopes

Myasthenia gravis (MG) is a T cell-regulated, antibody-mediated autoimmune disease. Two peptides representing sequences of the human acetylcholine receptor α-subunit, p195–212 and p259–271, previously were shown to stimulate the proliferation of peripheral blood lymphocytes of patients with MG and w...

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Bibliografiske detaljer
Main Authors: Faber-Elmann, Anat, Paas-Rozner, Miri, Sela, Michael, Mozes, Edna
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24371/
https://ncbi.nlm.nih.gov/pubmed/9826698
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