Altered peptide ligands act as partial agonists by inhibiting phospholipase C activity induced by myasthenogenic T cell epitopes

Myasthenia gravis (MG) is a T cell-regulated, antibody-mediated autoimmune disease. Two peptides representing sequences of the human acetylcholine receptor α-subunit, p195–212 and p259–271, previously were shown to stimulate the proliferation of peripheral blood lymphocytes of patients with MG and w...

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Bibliografiska uppgifter

I publikationen:	Proc Natl Acad Sci U S A
Huvudupphov:	Faber-Elmann, Anat, Paas-Rozner, Miri, Sela, Michael, Mozes, Edna
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	National Academy of Sciences 1998
Ämnen:	Biological Sciences
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24371/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826698/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14320
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