SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia

Waldenstrom macroglobulinemia (WM) is characterized by widespread involvement of the bone marrow at the time of diagnosis, implying continuous homing of WM cells into the marrow. The mechanisms by which trafficking of the malignant cells into the bone marrow has not been previously elucidated. In th...

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Bibliografski detalji
Glavni autori: Ngo, Hai T., Leleu, Xavier, Lee, Jack, Jia, Xiaoying, Melhem, Molly, Runnels, Judith, Moreau, Anne-Sophie, Burwick, Nicholas, Azab, Abdel Kareem, Roccaro, Aldo, Azab, Feda, Sacco, Antonio, Farag, Mena, Sackstein, Robert, Ghobrial, Irene M.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2008
Teme:
Neoplasia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435685/
https://ncbi.nlm.nih.gov/pubmed/18448868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-129395
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