DESIGNING PHASE 0 CANCER CLINICAL TRIALS

Phase 0 trials are designed primarily to evaluate the pharmacodynamic and/or pharmacokinetic properties of selected investigational agents prior to initiating more traditional phase 1 testing. One of the major objectives of phase 0 trials is to interrogate and refine a target or biomarker assay for...

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Autors principals: Murgo, Anthony J., Kummar, Shivaani, Rubinstein, Larry, Gutierrez, Martin, Collins, Jerry, Kinders, Robert, Parchment, Ralph E., Ji, Jiuping, Steinberg, Seth M., Yang, Sherry X., Hollingshead, Melinda, Chen, Alice, Helman, Lee, Wiltrout, Robert, Tomaszewski, Joseph E., Doroshow, James H.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435428/
https://ncbi.nlm.nih.gov/pubmed/18559582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4560
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