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Indole and other aromatic compounds activate the yeast TRPY1 channel
The yeast TRPY1 (Yvc1) channel is activated by membrane stretch to release vacuolar Ca(2+) into the cytoplasm upon osmotic upshock. Exogenously added indole greatly enhances the upshock-induced Ca(2+) release in vivo. Indole also reversibly activates the channels under patch clamp. A minimum of 10(-...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435385/ https://ncbi.nlm.nih.gov/pubmed/18396169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.03.046 |
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