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Loss-of-function Deletion of the Steroid Receptor Coactivaor-1 Gene in Mice Reduces Estrogen Effect on the Vascular Injury Response

OBJECTIVE: The steroid receptor coactivator-1 (SRC-1) is a transcriptional coactivator for nuclear receptors including estrogen receptor (ER). SRC-1 can interact with ER in an estrogen binding-dependent manner to potentiate the transcriptional activity of ER. Previous studies showed that SRC-1 was r...

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Autors principals: Yuan, Yuhui, Xu, Jianming
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435268/
https://ncbi.nlm.nih.gov/pubmed/17446438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.107.144477
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