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The deletion of the estrogen receptor α gene reduces susceptibility to estrogen-induced cholesterol cholelithiasis in female mice

Compelling evidence has demonstrated that estrogen is a critical risk factor for gallstone formation and enhances cholesterol cholelithogenesis through the hepatic estrogen receptor α (ERα), but not ERβ. To study the lithogenic mechanisms of estrogen through ERα, we investigated whether the deletion...

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Detaylı Bibliyografya
Yayımlandı:Biochim Biophys Acta
Asıl Yazarlar: de Bari, Ornella, Wang, Helen H., Portincasa, Piero, Liu, Min, Wang, David Q.-H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701041/
https://ncbi.nlm.nih.gov/pubmed/26232687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.07.020
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