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Transient blockage of the CD11d/CD18 integrin reduces contusion volume and macrophage infiltration after traumatic brain injury in rats

The early inflammatory response to traumatic brain injury (TBI) may result in secondary damage. The purpose of this study was to evaluate the effects of a transient treatment employing a blocking monoclonal antibody (mAb) to the CD11d/CD18 integrin on histopathological outcome and macrophage infiltr...

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Autors principals: Utagawa, Akira, Bramlett, Helen M., Daniels, Linda, Lotocki, George, Dekaban, Gregory, Weaver, Lynne C., Dietrich, W. Dalton
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435262/
https://ncbi.nlm.nih.gov/pubmed/18374312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.02.057
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