IL-15 serves as a co-stimulator in determining the activity of autoreactive CD8 Tcells in an experimental mouse model of graft vs. host like disease

To elucidate the mechanisms controlling peripheral tolerance, we established two transgenic (Tg) mouse strains expressing different levels of membrane-bound ovalbumin (mOVA) as a skin-associated self-antigen. When we transferred autoreactive TCR-Tg CD8 T cells (OT-I cells), keratin14 (K14)-mOVA(high...

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Detaylı Bibliyografya
Asıl Yazarlar: Miyagawa, Fumi, Tagaya, Yutaka, Kim, Brian S, Patel, Hiral J, Ishida, Kazuto, Ohteki, Toshiaki, Waldmann, Thomas A, Katz, Stephen I
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435206/
https://ncbi.nlm.nih.gov/pubmed/18606663
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