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Complementary roles of initiation factor 1 and ribosome recycling factor in 70S ribosome splitting

We demonstrate that ribosomes containing a messenger RNA (mRNA) with a strong Shine–Dalgarno sequence are rapidly split into subunits by initiation factors 1 (IF1) and 3 (IF3), but slowly split by ribosome recycling factor (RRF) and elongation factor G (EF-G). Post-termination-like (PTL) ribosomes c...

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Detalhes bibliográficos
Main Authors: Pavlov, Michael Y, Antoun, Ayman, Lovmar, Martin, Ehrenberg, Måns
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435134/
https://ncbi.nlm.nih.gov/pubmed/18497739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.99
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