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Dissection of spontaneous cytotoxicity by human intestinal intraepithelial lymphocytes: MIC on colon cancer triggers NKG2D-mediated lysis through Fas ligand

Human intestinal intraepithelial lymphocytes (IELs), which are T-cell receptor αβ(+) CD8(+) T cells located between epithelial cells (ECs), are likely to participate in the innate immune response against colon cancer. IELs demonstrate spontaneous cytotoxic (SC) activity specifically directed against...

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Bibliografski detalji
Glavni autori: Ebert, Ellen C, Groh, Veronika
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2434382/
https://ncbi.nlm.nih.gov/pubmed/18284469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02656.x
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