Spontaneous cytotoxicity of intestinal intraepithelial lymphocytes: clues to the mechanism.

Human intestinal intraepithelial lymphocytes (IEL) demonstrate target cell-restricted spontaneous cytotoxic (SC) activity that is due to CD2+CD3+CD8+CD16-CD56- effector cells; they kill epithelial cell (EC) tumours (such as DLD-1 colon cancer cells), but not natural killer (NK)-sensitive K-562 cells...

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Bibliographische Detailangaben
Hauptverfasser: Roberts, A I, O'Connell, S M, Biancone, L, Brolin, R E, Ebert, E C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534451/
https://ncbi.nlm.nih.gov/pubmed/8252812
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