RAS Signaling in Colorectal Carcinomas through Alteration of RAS, RAF, NF1, and/or RASSF1A

More than half of all colorectal carcinomas are known to exhibit an activated mitogen-activated protein kinase pathway. The NF1 gene, a negative regulator of KRAS, has not previously been examined in a series of colorectal cancer. In the present study, primary colorectal carcinomas stratified accord...

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Main Authors: Ahlquist, Terje, Bottillo, Irene, Danielsen, Stine A, Meling, Gunn I, Rognum, Torleiv O, Lind, Guro E, Dallapiccola, Bruno, Lothe, Ragnhild A
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2434205/
https://ncbi.nlm.nih.gov/pubmed/18592002
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