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p27(Kip1) nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells

The cellular mechanisms regulating intestinal differentiation are poorly understood. Sodium butyrate (NaBT), a short chain fatty acid, increases p27(Kip1) expression and induces cell cycle arrest associated with intestinal cell differentiation. Here, we show that treatment of intestinal-derived cell...

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Bibliografiske detaljer
Main Authors: Wang, Qingding, Zhou, Yuning, Wang, Xiaofu, Evers, B. Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432084/
https://ncbi.nlm.nih.gov/pubmed/18408738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2008.2
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