Plasma PCSK9 levels are significantly modified by statins and fibrates in humans

BACKGROUND: Proprotein convertase subtilisin kexin-like 9 (PCSK9) is a secreted glycoprotein that is transcriptionally regulated by cholesterol status. It modulates levels of circulating low density lipoprotein cholesterol (LDLC) by negatively regulating low density lipoprotein receptor (LDLR) level...

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Detalhes bibliográficos
Main Authors: Mayne, Janice, Dewpura, Thilina, Raymond, Angela, Cousins, Marion, Chaplin, Anna, Lahey, Karen A, LaHaye, Stephen A, Mbikay, Majambu, Ooi, Teik Chye, Chrétien, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432057/
https://ncbi.nlm.nih.gov/pubmed/18547436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-7-22
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