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Morphometry of the human substantia nigra in ageing and Parkinson's disease

To investigate the relation between the loss of substantia nigra (SN) neurons in normal ageing and Parkinson's disease (PD), we measured the total number and the cell body volume of pigmented (neuromelanin) neurons in the SN. We examined young (n = 7, mean age: 19.9), middle-aged (n = 9, mean a...

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Main Authors: Rudow, Gay, O'Brien, Richard, Savonenko, Alena V., Resnick, Susan M., Zonderman, Alan B., Pletnikova, Olga, Marsh, Laura, Dawson, Ted M., Crain, Barbara J., West, Mark J., Troncoso, Juan C.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431149/
https://ncbi.nlm.nih.gov/pubmed/18297291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-008-0352-8
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