Mild Cognitive Impairment and Asymptomatic Alzheimer Disease Subjects: Equivalent β-Amyloid and Tau Loads With Divergent Cognitive Outcomes

Older adults with intact cognition before death and substantial Alzheimer disease (AD) lesions at autopsy have been termed “asymptomatic AD subjects” (ASYMAD). We previously reported hypertrophy of neuronal cell bodies, nuclei, and nucleoli in the CA1 of the hippocampus (CA1), anterior cingulate gyr...

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Detalhes bibliográficos
Main Authors: Iacono, Diego, Resnick, Susan M., O’Brien, Richard, Zonderman, Alan B., An, Yang, Pletnikova, Olga, Rudow, Gay, Crain, Barbara, Troncoso, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062187/
https://ncbi.nlm.nih.gov/pubmed/24607960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000052
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