Conditional, genetic disruption of ciliary neurotrophic factor receptors reveals a role in adult motor neuron survival

Indirect evidence suggests that endogenous ciliary neurotrophic factor (CNTF) receptor signaling can promote motor neuron (MN) survival in the adult. If so, proper targeting of this signaling may selectively counteract the effects of adult MN diseases. However, direct evidence for CNTF receptor invo...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Nancy, Robitz, Rachel, Zurbrugg, Rebekah J, Karpman, Adam M, Mahler, Ashley M, Cronier, Samantha A, Vesey, Rachel, Spearry, Rachel P, Zolotukhin, Sergei, MacLennan, A John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2008
Schlagworte:
Research Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431126/
https://ncbi.nlm.nih.gov/pubmed/18588528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06298.x
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