Conditional, genetic disruption of ciliary neurotrophic factor receptors reveals a role in adult motor neuron survival

Indirect evidence suggests that endogenous ciliary neurotrophic factor (CNTF) receptor signaling can promote motor neuron (MN) survival in the adult. If so, proper targeting of this signaling may selectively counteract the effects of adult MN diseases. However, direct evidence for CNTF receptor invo...

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Detalhes bibliográficos
Main Authors: Lee, Nancy, Robitz, Rachel, Zurbrugg, Rebekah J, Karpman, Adam M, Mahler, Ashley M, Cronier, Samantha A, Vesey, Rachel, Spearry, Rachel P, Zolotukhin, Sergei, MacLennan, A John
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431126/
https://ncbi.nlm.nih.gov/pubmed/18588528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06298.x
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