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Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis
Lipin-1 deficiency in the mouse causes generalized lipodystrophy, characterized by impaired adipose tissue development and insulin resistance. Lipin-1 expression in differentiating preadipocytes is required for normal expression of adipogenic transcription factors, including peroxisome proliferator-...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2431106/ https://ncbi.nlm.nih.gov/pubmed/18362392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800061-JLR200 |
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