An Influenza A Vaccine Based on Tetrameric Ectodomain of Matrix Protein 2

Matrix protein 2 (M2) of influenza A is a tetrameric type III membrane protein that functions as a proton-selective channel. The extracellular domain (M2e) has remained nearly invariable since the first human influenza strain was isolated in 1933. By linking a modified form of the leucine zipper of...

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Bibliographic Details
Main Authors: De Filette, Marina, Martens, Wouter, Roose, Kenny, Deroo, Tom, Vervalle, Frederik, Bentahir, Mostafa, Vandekerckhove, Joel, Fiers, Walter, Saelens, Xavier
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431085/
https://ncbi.nlm.nih.gov/pubmed/18252707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800650200
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