Regulation of ApoB Secretion by the Low Density Lipoprotein Receptor Requires Exit from the Endoplasmic Reticulum and Interaction with ApoE or ApoB

Apolipoprotein B (apoB) is required for the hepatic assembly and secretion of very low density lipoprotein (VLDL). The LDL receptor (LDLR) promotes post-translational degradation of apoB and thereby reduces VLDL particle secretion. We investigated the trafficking pathways and ligand requirements for...

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Bibliografske podrobnosti
Main Authors: Blasiole, Daniel A., Oler, Angie T., Attie, Alan D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431081/
https://ncbi.nlm.nih.gov/pubmed/18272520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710457200
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