Deletion of the Protein Kinase A/Protein Kinase G Target SMTNL1 Promotes an Exercise-adapted Phenotype in Vascular Smooth Muscle

In vivo protein kinases A and G (PKA and PKG) coordinately phosphorylate a broad range of substrates to mediate their various physiological effects. The functions of many of these substrates have yet to be defined genetically. Herein we show a role for smoothelin-like protein 1 (SMTNL1), a novel in...

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Autores principales: Wooldridge, Anne A., Fortner, Christopher N., Lontay, Beata, Akimoto, Takayuki, Neppl, Ronald L., Facemire, Carie, Datto, Michael B., Kwon, Ashley, McCook, Everett, Li, Ping, Wang, Shiliang, Thresher, Randy J., Miller, Sara E., Perriard, Jean-Claude, Gavin, Timothy P., Hickner, Robert C., Coffman, Thomas M., Somlyo, Avril V., Yan, Zhen, Haystead, Timothy A. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431077/
https://ncbi.nlm.nih.gov/pubmed/18310078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708628200
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