Deletion of the Protein Kinase A/Protein Kinase G Target SMTNL1 Promotes an Exercise-adapted Phenotype in Vascular Smooth Muscle

In vivo protein kinases A and G (PKA and PKG) coordinately phosphorylate a broad range of substrates to mediate their various physiological effects. The functions of many of these substrates have yet to be defined genetically. Herein we show a role for smoothelin-like protein 1 (SMTNL1), a novel in...

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Main Authors: Wooldridge, Anne A., Fortner, Christopher N., Lontay, Beata, Akimoto, Takayuki, Neppl, Ronald L., Facemire, Carie, Datto, Michael B., Kwon, Ashley, McCook, Everett, Li, Ping, Wang, Shiliang, Thresher, Randy J., Miller, Sara E., Perriard, Jean-Claude, Gavin, Timothy P., Hickner, Robert C., Coffman, Thomas M., Somlyo, Avril V., Yan, Zhen, Haystead, Timothy A. J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431077/
https://ncbi.nlm.nih.gov/pubmed/18310078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708628200
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