Genome-wide Analysis Identifies Interleukin-10 mRNA as Target of Tristetraprolin

Tristetraprolin (TTP) is an RNA-binding protein required for the rapid degradation of mRNAs containing AU-rich elements. Targets regulated by TTP include the mRNAs encoding tumor necrosis factor-α, granulocyte-macrophage colony-stimulating factor, interleukin-2 (IL-2), and immediate early response 3...

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Главные авторы: Stoecklin, Georg, Tenenbaum, Scott A., Mayo, Thomas, Chittur, Sridar V., George, Ajish D., Baroni, Timothy E., Blackshear, Perry J., Anderson, Paul
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2008
Предметы:
RNA-Mediated Regulation and Noncoding Rnas
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431067/
https://ncbi.nlm.nih.gov/pubmed/18256032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709657200
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