Molecular Insights into the Biosynthesis of the F(420) Coenzyme

Coenzyme F(420), a hydride carrier, is found in Archaea and some bacteria and has crucial roles in methanogenesis, antibiotic biosynthesis, DNA repair, and activation of antitubercular compounds. CofD, 2-phospho-l-lactate transferase, catalyzes the last step in the biosynthesis of F(420)-0 (F(420) w...

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Bibliografiske detaljer
Main Authors: Forouhar, Farhad, Abashidze, Mariam, Xu, Huimin, Grochowski, Laura L., Seetharaman, Jayaraman, Hussain, Munif, Kuzin, Alexandre, Chen, Yang, Zhou, Weihong, Xiao, Rong, Acton, Thomas B., Montelione, Gaetano T., Galinier, Anne, White, Robert H., Tong, Liang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Enzyme Catalysis and Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431047/
https://ncbi.nlm.nih.gov/pubmed/18252724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710352200
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