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Activation of a Dormant ClpX Recognition Motif of Bacteriophage Mu Repressor by Inducing High Local Flexibility

The C-terminal domain (CTD) of bacteriophage Mu immunity repressor (Rep) regulates DNA binding by the N-terminal domain and degradation by ClpXP protease. Five residues at the Rep C terminus (CTD5) can serve as a ClpX recognition motif, but it is dormant unless activated, a state that can be induced...

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Sonraí Bibleagrafaíochta
Main Authors: Marshall-Batty, Kimberly R., Nakai, Hiroshi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431027/
https://ncbi.nlm.nih.gov/pubmed/18230617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705508200
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