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Dissociation from the Oligomeric State Is the Rate-limiting Step in Fibril Formation by κ-Casein

Amyloid fibrils are aggregated and precipitated forms of protein in which the protein exists in highly ordered, long, unbranching threadlike formations that are stable and resistant to degradation by proteases. Fibril formation is an ordered process that typically involves the unfolding of a protein...

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Autores principales: Ecroyd, Heath, Koudelka, Tomas, Thorn, David C., Williams, Danielle M., Devlin, Glyn, Hoffmann, Peter, Carver, John A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431022/
https://ncbi.nlm.nih.gov/pubmed/18245081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709928200
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