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microRNA-155 is a negative regulator of Activation Induced Cytidine deaminase
B lymphocytes perform somatic hypermutation (SHM) and class switch recombination (CSR) of the immunoglobulin locus to generate an antibody repertoire diverse in both affinity and function. These somatic diversification processes are catalyzed by activation-induced cytidine deaminase (AID), a potent...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430982/ https://ncbi.nlm.nih.gov/pubmed/18450484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.03.015 |
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