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Using the longest significance run to estimate region-specific p-values in genetic association mapping studies

BACKGROUND: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increase in the density of available genetic markers, necessitating an increase in the number of association tests required for...

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Detalhes bibliográficos
Main Authors: Lian, Ie-Bin, Lin, Yi-Hsien, Lin, Ying-Chao, Yang, Hsin-Chou, Chang, Chee-Jang, Fann, Cathy SJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430975/
https://ncbi.nlm.nih.gov/pubmed/18503718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-246
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