Expression of Brugmansia candida Hyoscyamine 6beta-Hydroxylase gene in Saccharomyces cerevisiae and its potential use as biocatalyst

BACKGROUND: Tropane alkaloids, mainly hyoscyamine and scopolamine, are widely used in medicine due to their anticholinergic activity. Scopolamine has a higher demand being the more valuable alkaloid due to its fewer side effects and higher physiological activity. Anisodamine (6β-hydroxyhyoscyamine)...

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Autors principals: Cardillo, Alejandra B, Talou, Julián Rodríguez, Giulietti, Ana M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430943/
https://ncbi.nlm.nih.gov/pubmed/18505565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-7-17
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