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Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with a Novel Mode of Binding

The LytTR domain is a DNA-binding motif found within the AlgR/AgrA/LytR family of transcription factors that regulate virulence factor and toxin gene expression in pathogenic bacteria. This previously uncharacterized domain lacks sequence similarity with proteins of known structure. The crystal stru...

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Hlavní autoři: Sidote, David J., Barbieri, Christopher M., Wu, Ti, Stock, Ann M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430735/
https://ncbi.nlm.nih.gov/pubmed/18462677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.02.011
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